Short answer
No, not in itself. Medicines such as semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro) are allowed when prescribed for diabetes, obesity or weight-related health risks and used under medical supervision. Using them without need, buying them from unregulated sellers, or using them in a way that harms you is not allowed. The four schools agree on the principle.
Taking a prescribed medicine to treat diabetes or obesity is permitted. Using a drug in a way that causes significant harm, or obtaining it from unsafe sources or by deceit, is not, because harming the body is forbidden.
The four schools agree on this.
Explanation
Obesity and type 2 diabetes raise the risk of heart disease, stroke and other illness, and the Prophet ﷺ told people to seek treatment. If your doctor prescribes one of these injections as part of a plan, taking it is like taking any other medicine. The Sunnah also teaches moderation in eating: a third for food, a third for drink and a third for breath.
- Harm. These drugs have side effects, some serious. Using them without a doctor, or at someone else's dose, risks your health, and there is to be no harm and no returning harm.
- Unsafe sources. Counterfeit and unlicensed versions are sold online. Buying unregulated medicine puts your health at risk and may break the law.
- Vanity alone. Taking a powerful drug to lose a few kilos when your weight is healthy is hard to justify when it carries real risk.
- Deceit. Lying to a doctor or insurer to get it is haram.
On ingredients: the active drugs are made in laboratories, and their published ingredients do not include pork or drinking alcohol. Formulations differ between products and countries, so ask your pharmacist for the full list if you want to be sure.
Injections do not break the fast in the Hanafi school, so a weekly dose on a fasting day is fine; ask your doctor about dosing in Ramadan, since these drugs reduce appetite and fluid intake. See what breaks your fast and is taking medicine against tawakkul.
Ask a mufti about your own case. This answer explains the general ruling. When the details of your situation matter, as they do here, ask a qualified mufti and give them the full facts. Where to ask a scholar.
The evidence
Quran, Surah Al-A'raaf 7:31
۞ يَٰبَنِىٓ ءَادَمَ خُذُوا۟ زِينَتَكُمْ عِندَ كُلِّ مَسْجِدٍۢ وَكُلُوا۟ وَٱشْرَبُوا۟ وَلَا تُسْرِفُوٓا۟ ۚ إِنَّهُۥ لَا يُحِبُّ ٱلْمُسْرِفِينَ ﴿٣١﴾
O children of Adam, take your adornment at every masjid, and eat and drink, but be not excessive. Indeed, He likes not those who commit excess.
Moderation in eating is the Quran's teaching.
Quran, Surah Al-Baqara 2:195
وَأَنفِقُوا۟ فِى سَبِيلِ ٱللَّهِ وَلَا تُلْقُوا۟ بِأَيْدِيكُمْ إِلَى ٱلتَّهْلُكَةِ ۛ وَأَحْسِنُوٓا۟ ۛ إِنَّ ٱللَّهَ يُحِبُّ ٱلْمُحْسِنِينَ ﴿١٩٥﴾
And spend in the way of Allah and do not throw [yourselves] with your [own] hands into destruction [by refraining]. And do good; indeed, Allah loves the doers of good.
Using medicine in a harmful way is forbidden.
Jami' at-Tirmidhi 2380
Grading to be checked... ما ملأ آدمي وعاء شرا من بطن ...
"A human being fills no vessel worse than his stomach."
The Sunnah encourages eating less.
Sunan Ibn Majah 2340
Graded sahih... لا ضرر ولا ضرار ...
"There is to be no harm and no returning harm."
Harmful or unsupervised use is forbidden.
Where the ruling is recorded
- al-Ashbah wa al-Naza'ir (Ibn Nujaym), The fifth legal maxim: harm is to be removed. Treatment removes harm, while harmful use must be avoided.
- al-Fatawa al-Hindiyya, Kitab al-Karahiyya, chapter on treatment and remedies (al-tadawi wa al-mu'alajat). Treatment with lawful medicine is permitted.
Checked by our team. For a more accurate answer to your own situation, consult a scholar. Quran translation by Sahih International. Hadith Arabic from the standard editions of the six books and the Muwatta, with gradings as recorded there; the English is our own rendering. Spotted a mistake? Tell us.